The gene vdr encodes a transcriptional regulator that regulates the expression of nutritional D-dependent family genes. The proteins contains a zinc-finger DNA-binding domain, a transcriptional activation domain and a ligand binding web page. The protein is a member of the steroid and thyroid junk receptor superfamily.
The T > C allele of the FokI polymorphism at the translation start site of vdr results in a shortened protein that lacks a functional activation domain name. It is seen as decreased products to transcription factor IIB and decreased transactivation activity. The consistency of the variant allele varies among cultural groups. It has been implicated in variations in calcium consumption, bone mineral density (BMD), and anthropometric measurements.
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Venture capitalists and private value firms use VDR software to create a highly-secure pipeline of information with partners, portfolio companies, auditors, and third parties. They also utilize platform to regulate client documentation relevant to investment prospects.